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Keynote 775 publication8/1/2023 ![]() ![]() "The publication of this study in the New England Journal of Medicine reflects the importance of our joint research in exploring the potential of the LENVIMA plus KEYTRUDA combination." share in addressing the unmet needs of people living with difficult-to-treat cancers, including advanced endometrial carcinoma," said Corina Dutcus, M.D., Senior Vice President, Clinical Research, Oncology Business Group at Eisai Inc. "The Phase 3 Study 309/KEYNOTE-775 trial demonstrates the ongoing commitment that Eisai and Merck & Co., Inc., Kenilworth, N.J., U.S.A. ![]() and other countries around the world, where it became the first immunotherapy and tyrosine kinase inhibitor combination approved for these patients." "KEYNOTE-775/Study 309 is an important Phase 3 study that supported recent approvals of KEYTRUDA plus LENVIMA for certain types of advanced endometrial carcinoma in the U.S. Gregory Lubiniecki, Vice President, Oncology Clinical Research, Merck Research Laboratories. "While rates of endometrial carcinoma continue to rise globally, patients with advanced or recurrent disease have limited options available to them once the disease progresses following platinum-based chemotherapy," said Dr. Objective response rate (ORR) data and additional detailed efficacy and safety data, including subgroup analyses, are also featured in the publication. The publication includes previously reported data that was first presented in an oral plenary session at the virtual Society of Gynecologic Oncology (SGO) 2021 Annual Meeting on Women's Cancer.(1) Results showed that the LENVIMA plus KEYTRUDA combination demonstrated statistically significant improvements in the dual primary endpoints of overall survival (OS) and progression-free survival (PFS) compared to chemotherapy. versus chemotherapy (treatment of physician's choice of doxorubicin or paclitaxel) for patients with advanced endometrial carcinoma following at-least one prior platinum-based regimen in any setting. The pivotal study evaluated the combination of LENVIMA, the orally available multiple receptor tyrosine kinase inhibitor discovered by Eisai, plus KEYTRUDA, the anti-PD-1 therapy from Merck & Co., Inc., Kenilworth, N.J., U.S.A. (known as MSD outside the United States and Canada) today announced the publication of results from the Phase 3 Study 309/KEYNOTE-775 trial in the Januedition of the New England Journal of Medicine. TOKYO, (JCN Newswire) - Eisai and Merck & Co., Inc., Kenilworth, N.J., U.S.A.
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![]() Now, we have 3 files in the working tree: " Hello.java", " Hello.class" and " README.md". This is the README file for the Hello-world project. It is also highly recommended to provide a " README.md" file (a text file in a so-called "Markdown" syntax such as " GitHub Flavored Markdown") to describe your project: // README.md ("Hello, world from GIT!") Ĭompile the " Hello.java" into " Hello.class" (or " Hello.cpp" or " Hello.c" into " Hello.exe"). Let's start a programming project under the working directory called " hello-git", with one source file " Hello.java" (or " Hello.cpp", or " Hello.c") as follows: // Hello.java Setup the Working Directory for a New Project We shall begin with "Starting your own project" and cover "Cloning" later " Clone a Project from a Remote Repo". Cloning an existing project from a GIT host.There are 2 ways to start a Git-managed project: The GIT manual is bundled with the software (under the " doc" directory), and also available online. The best way to get help these days is certainly googling. checkout, branch, merge, push, fetch, pull.status, log, diff, grep, show: show status.init, clone, config: for starting a Git-managed project.To issue a command, start a "Terminal" (for Ubuntu/Mac) or "Git Bash" (for Windows): Git provides a set of simple, distinct, standalone commandsĭeveloped according to the "Unix toolkit" philosophy - build small, interoperable tools. You can issue " git config -list" to list the settings: $ git config -global user.email " settings are kept in " /etc/gitconfig" (of the GIT installed directory) and " /.gitconfig" (of the user's home directory. $ git config -global user.name " your-name" Set up your username and email (to be used in labeling your commits) Issue " git config" command (for Windows, run "Git Bash" from the Git installed directory. For Ubuntu, issue command " sudo apt-get install git".įor Windows, use the "Git Bash" command shell bundled with Git Installer to issue commands.For Windows and Mac, download the installer from and run the downloaded installer.You need to setup Git on your local machine, as follows: Distributed VCS (DVCS): GIT, Merurial, Bazaar, Darcs.Centralized Client-Server Version Control System (CVCS): CVS (Concurrent Version System), SVN (Subversion) and Perforce.The standalone and legacy Unix's RCS (Revision Control System).GIT is a Distributed Version Control System (DVCS). Git was initially designed and developed by Linus Torvalds, in 2005, to support the development of the Linux kernel. It facilitates collaboration between team members, and serves as a project management tool.It lets you revert back to a specific version, if the need arises. It is a living archive of all historical revisions.The Repository serves as the backup (in case of code changes or disk crash).It records changes to files at so-called commits in a log so that you can recall any file at any commit point. A VCS serves as a Repository (or repo) of program codes, including all the historical revisions. GIT is a Version Control System (VCS) (aka Revision Control System (RCS), Source Code Manager (SCM)).
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Fullmetal alchemist greed armor8/1/2023 ![]() There’s enough hook and bait there to make you think about what is going to happen in the next volume. A little bit of misdirection and you’re setting Scar up for a shift in alignment in the future! Final ThoughtsĪnother great edition of Fullmetal Alchemist! We got some nice story advancement and now we’ve opened up a bigger mystery involving the military. ![]() It’s a soft and subtle development cue placed by Arakawa. He now only needs to realize that there is a way back. I liked how they built some sympathy for Scar here… like he has no path for redemption but the fact that he just admitted that there’s no turning back means he’s already begun his redemption. He is reunited with his master who takes pity on him when Scar attacks his attackers and says that he’s too far down the path to turn back now. Lastly, it looks like not Ishvalans care for each other as Scar was attacked by his very own people all because of the bounty that has been placed on his head. That’s about as much hinting as I’ll do today. It’s a pretty interesting reveal that makes you think more about some of the types of characters that are in the series and their alignments. In the chance that this is your first time reading the series, though. As popular as this series is… if you’re reading the Fullmetal Edition, chances are you doing so as a refresher so you already know the secret in question. ![]() Of course, this is only for people who have never read the series. Of course, we got the big reveal with Fuhrer King Bradley but I won’t spoil it. As weird as that sounds, it was a cool yin/yang balance to him. He had a duality of being noble yet underhanded at the same time. The fact that he kept ordering Al and Ed to be roughed up and not killed showed that he was very calculated in his moves and knew full well their value and worth… another sign of being greedy. With a name like Greed, the desire to know that fits right in with his personality and his namesake. Having a soul transmuted into something would make him immortal and he was highly interested in that information. While he is a homunculus, he can still be killed and isn’t a true immortal. He simply wanted information about soul transmutation. Despite the battle that took place, Greed really did try to keep everything as civil as possible. While it’s a small step, it’s still a step in the right direction. Still, Ed and Al are now one step closer to figuring out how to get their bodies back. ![]() Not much in the way of development for Ed but Alphonse ended up regaining his memories of when his soul was transmuted into his armor however, those memories are not complete. The volume was mostly taken up by the action but there was some great character development here as well! Characters The mystery gets deeper and deeper and now it looks as if there’s some collusion going on with the military as well. This brings our volume to a close.įirst Lust, Envy, and Sloth and now we’re introduced to Greed. Meanwhile, we get caught up with Winry who is confronted by our old friend Barry the Chopper! She easily takes care of him and calls Colonel Mustang to report that she captured him. Bradley ends up taking on Greed by himself and that’s when we learn a bit of a secret about Bradley!Īfter the battle is over, Ed begins to become a bit suspicious about the military. Ed refuses to make a deal with Greed and the scene turns into a war zone. Bradley, Armstrong and a platoon of military members follow suit. Once they all know the details, Ed heads off alone to go find Alphonse. Izumi gets Ed once he returns from his assessment however, Ed was followed by Fuhrer King Bradley and Major Armstrong. Izumi gets worried and tracks them down but Greed makes it clear that he just wants to make a deal and needs information from Ed in order to close said deal. He’s kidnapped and that’s when we are introduced another homunculus by the name of Greed who wants to know how Alphonse had his soul transmuted onto his armor. Meanwhile, Alphonse heads out and ends up getting approached by some shady people. As Edward was about to leave, he remembers that he needs to take his assessment to remain a state alchemist and heads to a nearby branch office. The fifth volume of Fullmetal Alchemist Fullmetal Edition ends the flashback scene of how Edward and Alphonse ended up in their current state. Title: Fullmetal Alchemist: Fullmetal Edition Vol.
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Skype web app plugin download8/1/2023 ![]()
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